A club insider told Footballghana.com that the dynamic midfielder, 25, has been ruled out of the tournament after suffering an injury against Athletico Madrid on Thursday.
As he gets ready to formally reveal the list on Monday morning, Otto Addo is now planning to make a few last-minute adjustments to his team.
Ghana will begin training in Abu Dhabi and play Switzerland on November 17 before departing for the competition in Doha on November 19.
At Stadium 974 in Doha, Ghana’s campaign will get underway against Portugal on November 24.
The Black Stars are back in action four days later when they play South Korea at Al Rayyan’s Education City Stadium.
At Al Janoub Stadium in Al Wakrah, Ghana will conclude their exciting group stage journey with their much awaited matchup with Uruguay.
The Black Stars will be seeking to improve on their performance in Qatar after exiting the group stage during the 2014 World Cup in Brazil. The Black Stars lost out on the most recent tournament, which was held in Russia in 2018.